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Medical Channel Asia Latest Questions

acneman

I (20M) have had really bad acne since I was a teenager. It hasn't improved at all over the years, but is it true that taking Accutane can help?

I (20M) have had really bad acne since I was a teenager. It hasn’t improved at all over the years, but is it true that taking Accutane can help?

3 Answers

  1. The following answer is provided by HELF AI (www.HELF.co), a next-gen AI backend built to power the health & wellness industry.

    Accutane is indeed a highly effective treatment for severe acne, particularly nodulocystic acne or acne that has not responded to other treatments. It works by significantly reducing the size and activity of sebaceous glands, decreasing sebum production, and normalizing skin cell turnover, which helps prevent the formation of new acne lesions.

    Key Considerations for Accutane Use:

    1. Efficacy: Accutane is often considered when other treatments, such as topical therapies and oral antibiotics, have failed. It has a high success rate, with many patients experiencing long-term remission of acne after a single course.

    2. Course Duration: Treatment typically lasts 15-20 weeks, but the duration can vary based on the dose and individual response. The goal is to reach a cumulative dose of 120-150 mg/kg to maximize the likelihood of long-term remission.

    3. Side Effects: While effective, Accutane is associated with a range of potential side effects. Common side effects include dry skin, lips, and eyes, as well as increased sensitivity to the sun. More serious, but less common, side effects can include mood changes, liver enzyme alterations, and lipid profile changes. Regular monitoring by a healthcare provider is essential.

    4. Teratogenicity: Accutane is highly teratogenic, meaning it can cause severe birth defects. Although this is not a direct concern for you, it underscores the importance of strict adherence to guidelines, especially for female patients who must use effective contraception.

    5. Psychological Effects: There have been reports of mood changes, including depression and anxiety, in some patients taking Accutane. While a direct causal relationship has not been definitively established, it is crucial to monitor mental health during treatment.

    6. Monitoring: Regular follow-up appointments are necessary to monitor for side effects and adjust dosing as needed. Blood tests are typically performed to check liver function and lipid levels.

    Practical Advice:

    Consultation: It is important to have a thorough discussion with a dermatologist to evaluate whether Accutane is appropriate for your specific case. They will assess the severity of your acne, previous treatment responses, and any potential contraindications.

    Adherence: If prescribed Accutane, adherence to the treatment regimen and follow-up appointments is crucial to ensure safety and effectiveness.

    Lifestyle Adjustments: During treatment, you may need to adjust skincare routines to manage dryness and protect your skin from sun exposure.

    In summary, Accutane can be a highly effective option for treating severe acne, but it requires careful consideration and management due to its potential side effects. A dermatologist can provide personalized guidance and ensure that the treatment is both safe and effective for you.

  2. Hi, I’m Dr. Paul Yow – Director of Aesthetic Medicine at Eagle Aesthetics and Surgery and I hope the following answer will be useful to you!
    Accutane or oral isotretinoin is an vitamin A derivative and is an effective treatment for moderate to severe forms of acne.
    It works by:
    (i) reducing the size and activity of the skin’s oil glands.
    (ii) reducing bacteria on the skin
    (iii) preventing excessive buildup of dead skin cells to clog pores
    (iv) reducing the inflammation associated with acne
    The issues to note with acutance would be the need for regular blood tests to check on the liver and cholesterol levels, the side effect of dryness due to lessen sebum or oil production as well as an adherence to the completion of the course calculated by your doctor.
    Aside from acutance, there are a wide range of treatment options for acne ranging from oral antibiotics, topical medications and skin care to lasers and microneedling and I would advised seeing someone to discuss these options as well as your suitability for acutance.
    If you have any concerns about your options, feel free to reach out for more information. Happy to help answer any more questions!

    Dr. Paul Yow
    Director of Aesthetic Medicine
    Eagle Aesthetics & Surgery
    Instagram: Dr. Paul Yow

    The information provided on this forum is for educational purposes only and not intended as medical advice. Please consult a healthcare provider for any medical concerns, diagnosis or treatment.

  3. Dr. Joyce Lim (Joyce Lim Skin & Laser Clinic)
    Dr. Lim is a dermatologist who treats skin, hair and nail problems in both adults and children. Besides medical dermatology, Dr. Lim has the expertise to treat aesthetic skin problems as well as perform laser and skin surgery. In addition to her clinical practice, Dr. Lim conducts teaching sessions for dermatologists and aesthetic doctors.
    This answer was edited.

    I hear you – it can be frustrating dealing with persistent acne, especially when it doesn’t seem to improve with time. Yes, isotretinoin (Accutane) is an effective treatment option for moderate to severe acne that hasn’t responded well to other treatments. It works by shrinking the oil glands in your skin, which helps reduce oil production, clogged pores, and inflammation. Many people see significant, long-lasting improvement after taking the medication.

    Dermatologists like myself typically recommend it when conventional acne treatments are not effective. It is also useful for nodulocystic acne. Nowadays it is given in a low dose regime to reduce side-effects without compromising efficacy 

    This medication can have potential side effects:

    • Mucosal areas like the lips and eyes as well as the skin  can become very dry when on isotretinoin and so you need to use moisturisers and lip balm
    • Isotretinoin can cause increased sun sensitivity and you need to use a sunscreen when outdoors
    • The medication can cause serious birth defects, so female patients must use strict contraception while on it.

    Regular blood tests may be needed especially if you are on high doses.

    Since your acne has persisted for years without improvement, it’s a good idea to consult a dermatologist. A dermatologist is a skin expert in acne who can assess your acne severity, identify any trigger factors and discuss the treatment options with you.  If you need isotretinion, your dermatologist can guide you through the treatment plan and possible side-effects.  

    In the meantime, you can also manage your acne by using skincare products for acne-prone skin, reducing foods in your diet that you notice may cause acne flare-ups, and managing stress (which can also cause acne flares).

     

    Wishing you all the best in your skincare journey!

     

    Dr Joyce Lim

    Consultant Dermatologist

    Joyce Lim Skin & Laser Clinic

    http://www.joycelim.com

     

    The information provided on this forum is for educational purposes only and not intended as medical advice. Please consult a healthcare provider for any medical concerns, diagnosis or treatment.

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