I (20M) have had really bad acne since I was a teenager. It hasn’t improved at all over the years, but is it true that taking Accutane can help?
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Hi, I’m Dr. Paul Yow – Director of Aesthetic Medicine at Eagle Aesthetics and Surgery and I hope the following answer will be useful to you!
Accutane or oral isotretinoin is an vitamin A derivative and is an effective treatment for moderate to severe forms of acne.
It works by:
(i) reducing the size and activity of the skin’s oil glands.
(ii) reducing bacteria on the skin
(iii) preventing excessive buildup of dead skin cells to clog pores
(iv) reducing the inflammation associated with acne
The issues to note with acutance would be the need for regular blood tests to check on the liver and cholesterol levels, the side effect of dryness due to lessen sebum or oil production as well as an adherence to the completion of the course calculated by your doctor.
Aside from acutance, there are a wide range of treatment options for acne ranging from oral antibiotics, topical medications and skin care to lasers and microneedling and I would advised seeing someone to discuss these options as well as your suitability for acutance.
If you have any concerns about your options, feel free to reach out for more information. Happy to help answer any more questions!
Dr. Paul Yow
Director of Aesthetic Medicine
Eagle Aesthetics & Surgery
Instagram: Dr. Paul Yow
The information provided on this forum is for educational purposes only and not intended as medical advice. Please consult a healthcare provider for any medical concerns, diagnosis or treatment.
Accutane is indeed a highly effective treatment for severe acne, particularly nodulocystic acne or acne that has not responded to other treatments. It works by significantly reducing the size and activity of sebaceous glands, decreasing sebum production, and normalizing skin cell turnover, which helps prevent the formation of new acne lesions.
Key Considerations for Accutane Use:
1. Efficacy: Accutane is often considered when other treatments, such as topical therapies and oral antibiotics, have failed. It has a high success rate, with many patients experiencing long-term remission of acne after a single course.
2. Course Duration: Treatment typically lasts 15-20 weeks, but the duration can vary based on the dose and individual response. The goal is to reach a cumulative dose of 120-150 mg/kg to maximize the likelihood of long-term remission.
3. Side Effects: While effective, Accutane is associated with a range of potential side effects. Common side effects include dry skin, lips, and eyes, as well as increased sensitivity to the sun. More serious, but less common, side effects can include mood changes, liver enzyme alterations, and lipid profile changes. Regular monitoring by a healthcare provider is essential.
4. Teratogenicity: Accutane is highly teratogenic, meaning it can cause severe birth defects. Although this is not a direct concern for you, it underscores the importance of strict adherence to guidelines, especially for female patients who must use effective contraception.
5. Psychological Effects: There have been reports of mood changes, including depression and anxiety, in some patients taking Accutane. While a direct causal relationship has not been definitively established, it is crucial to monitor mental health during treatment.
6. Monitoring: Regular follow-up appointments are necessary to monitor for side effects and adjust dosing as needed. Blood tests are typically performed to check liver function and lipid levels.
Practical Advice:
– Consultation: It is important to have a thorough discussion with a dermatologist to evaluate whether Accutane is appropriate for your specific case. They will assess the severity of your acne, previous treatment responses, and any potential contraindications.
– Adherence: If prescribed Accutane, adherence to the treatment regimen and follow-up appointments is crucial to ensure safety and effectiveness.
– Lifestyle Adjustments: During treatment, you may need to adjust skincare routines to manage dryness and protect your skin from sun exposure.
In summary, Accutane can be a highly effective option for treating severe acne, but it requires careful consideration and management due to its potential side effects. A dermatologist can provide personalized guidance and ensure that the treatment is both safe and effective for you.