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Cardiogenic shock is the leading cause of death amongst patients hospitalized with acute myocardial infarction. Immediate revascularization of the culprit lesion is the only treatment available but mortality still remains high. The use of extracorporeal life support (ECLS), which enables full circulatory and respiratory support, have increased with the aim to achieve haemodynamic stabilization in patients with severe or rapidly deteriorating infarct-related cardiogenic shock. 

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IMbrella A, an extension of the Phase III IMpower133 study, demonstrates the potential for a durable overall survival benefit with Tecentriq plus chemotherapy in extensive-stage small cell lung cancer (ES-SCLC)
IMbrella A data build on the previously reported IMpower133 trial, which was the first clinically meaningful advance in the treatment of ES-SCLC in more than twenty years

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As postpartum depression shadows the joy of many new mothers, Zuranolone emerges as a promising oral alternative, addressing the constraints of the current intravenous treatment.

Postpartum depression (PPD) occurs in about 6.5% to 20% of women[1]. While the birth of a child is traditionally associated with happiness and celebration, some find themselves grappling with a profound sense of sadness, anxiety, and emotional turmoil in the weeks or months following childbirth. Risk factors include depression prior to or during pregnancy, experiencing stressful events during pregnancy, low levels of social and familial support, obstetric complications etc. Not only does untreated PPD affect the mother, it can adversely impact the infant as well as their partners.  Women with PPD are at a higher risk of alcohol and/or substance abuse, while negative maternal-infant interactions have been known to affect cognitive functioning and emotional development in children [2]. 

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