Browsing: Cardiovascular

With the emergence and increasing popularity of glucagon-like peptide 1 (GLP-1) agonists for the treatment of obesity in recent years, it might be worth investigating if these agents are able to reduce the cardiovascular risks associated with overweight and obesity, especially since they have been shown to reduce risk of major adverse cardiovascular events in patients with type 2 diabetes who are at high cardiovascular risk.

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Summary: The recent MULTISTARS AMI trial reveals significant findings, indicating that immediate multivessel PCI is non-inferior to staged procedures for patients with STEMI and multivessel coronary artery disease. This approach potentially alters the course of treatment by reducing serious cardiac events, thereby influencing guidelines on the optimal timing for such interventions.

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A recent study shows that delaying sleep by just 90 minutes each night damages blood vessels, contributing to the development of cardiovascular diseases. A study conducted in the University of Columbia recently showed that mild sleep restriction among female individuals causes an increase in oxidative stress in blood vessels. It is the first direct evidence linking mild, chronic sleep deficits to causing heart disease.

Iron deficiency is present in 50% of the patients with heart failure and it is associated with worse symptoms and outcomes [1]. There have been a few studies analysing the benefit of intravenous (IV) ferric carboxymaltose in heart failure with iron deficiency. In the AFFIRM-AHF [2] trial, administration of IV ferric carboxymaltose reduced the risk of cardiovascular death and total hospitalisations for heart failure in patients hospitalized for acute heart failure.

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World Heart Day stands as a universal reminder for us to ponder upon the significance of our hearts, not just as an organ, but as a symbol of unity and life. It’s more than just hearing and feeling the heartbeat; it’s about understanding the vitality of making the right decisions and acting courageously for the betterment of humanity and nature. In a special way, “For Every Heart” becomes a mantra, bringing the spotlight onto the beneficiaries and personalising this noble cause.

Cardiogenic shock is the leading cause of death amongst patients hospitalized with acute myocardial infarction. Immediate revascularization of the culprit lesion is the only treatment available but mortality still remains high. The use of extracorporeal life support (ECLS), which enables full circulatory and respiratory support, have increased with the aim to achieve haemodynamic stabilization in patients with severe or rapidly deteriorating infarct-related cardiogenic shock. 

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