Browsing: Medication & Drugs

Intravenous Iron In Ambulant Patients With Heart Failure – Do We See The Same Benefits?

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Iron deficiency is present in 50% of the patients with heart failure and it is associated with worse symptoms and outcomes [1]. There have been a few studies analysing the benefit of intravenous (IV) ferric carboxymaltose in heart failure with iron deficiency. In the AFFIRM-AHF [2] trial, administration of IV ferric carboxymaltose reduced the risk of cardiovascular death and total hospitalisations for heart failure in patients hospitalized for acute heart failure.

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Thailand PM Vows Tighter Medical Cannabis Control amidst Sprouting Dispensaries

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In a bold move, Thailand’s Prime Minister, Srettha Thavisin, announced a resolve to revise the country’s cannabis policy. Thavisin intends to move the country towards only allowing medical cannabis use within six months. This comes after a surge of nearly 6,000 cannabis dispensaries sprouted across the nation following its groundbreaking decriminalisation of cannabis a year ago, making it the first in Asia to do so.

Roche reports positive five-year survival outcomes for extensive-stage small cell lung cancer

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IMbrella A, an extension of the Phase III IMpower133 study, demonstrates the potential for a durable overall survival benefit with Tecentriq plus chemotherapy in extensive-stage small cell lung cancer (ES-SCLC)
IMbrella A data build on the previously reported IMpower133 trial, which was the first clinically meaningful advance in the treatment of ES-SCLC in more than twenty years

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Zuranolone – Another Hope For Postpartum Depression

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As postpartum depression shadows the joy of many new mothers, Zuranolone emerges as a promising oral alternative, addressing the constraints of the current intravenous treatment.

Postpartum depression (PPD) occurs in about 6.5% to 20% of women[1]. While the birth of a child is traditionally associated with happiness and celebration, some find themselves grappling with a profound sense of sadness, anxiety, and emotional turmoil in the weeks or months following childbirth. Risk factors include depression prior to or during pregnancy, experiencing stressful events during pregnancy, low levels of social and familial support, obstetric complications etc. Not only does untreated PPD affect the mother, it can adversely impact the infant as well as their partners.  Women with PPD are at a higher risk of alcohol and/or substance abuse, while negative maternal-infant interactions have been known to affect cognitive functioning and emotional development in children [2]. 

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