Ozempic Face: Look Whats Happening to Hollywood Stars

Women World Kelly Osbourne Ozempic Face

The cosmetic consequences of using the diabetes medication Ozempic for off-label weight loss are becoming increasingly visible. Dubbed “Ozempic face,” this phenomenon describes the rapid ageing and sagging of facial skin seen in some users.

As the drug gains popularity for its weight-loss benefits, its side effects raise concerns among medical professionals and the public alike.

Understanding Ozempic

Originally developed for type 2 diabetes management, Ozempic, or semaglutide, is administered through an injectable pen. Doctors typically recommend injecting it once a week under the skin in the thigh, upper arm, or abdomen. Despite its intended use, Ozempic has found a fervent following among those seeking weight loss, leading to shortages due to its off-label use.

What is Ozempic Face?

The term “Ozempic face” was coined by celebrity dermatologist Dr. Paul Jarrod Frank after observing significant changes in patients using the drug for weight loss. Characteristics of “Ozempic face” include increased wrinkles, sagging skin, and a gaunt appearance due to rapid and pronounced loss of facial fat.

The Science Behind the Effects

Ozempic functions as an incretin mimetic, enhancing the pancreas’s insulin release in response to high blood sugar levels. Furthermore, as a glucagon-like peptide-1 receptor agonist, it suppresses appetite and slows gastric emptying, which contributes to weight loss. This rapid reduction in body weight, particularly noticeable in facial fat, leads to a decrease in the structural proteins like collagen and elastin, causing skin to lose its elasticity and youthful appearance.

Celebrity Impact and Public Perception

The phenomenon of the “Ozempic face” is not just a medical curiosity but has become a visible trend among celebrities, influencing public perceptions of beauty and ageing. High-profile cases in Hollywood, where stars appear suddenly with gaunter and more aged features, have sparked discussions about the health implications and societal pressures driving the use of weight loss drugs. Celebrities like Sharon Osbourne, Scott Disick and others have been noted for their altered appearances, which are speculated to be due to Ozempic usage.

Health Concerns and Side Effects

While Ozempic is generally safe when used under medical supervision, its side effects can range from mild to severe. Common issues include nausea, vomiting, and gastrointestinal discomfort, while more severe reactions may involve vision changes, kidney problems, and even an increased risk of thyroid cancer. The drug’s impact extends beyond the cosmetic, with potential serious health consequences that warrant cautious use.

Addressing Ozempic Face

To combat the undesirable effects of “Ozempic face,” doctors may recommend various interventions. Lifestyle modifications to stabilize weight, alongside medical treatments like facial fillers, can help mitigate the effects of ageing. However, the ethical implications of using a diabetes drug for weight loss highlight a growing issue in medical and beauty standards, emphasizing the need for strict guidelines and ethical practices in its distribution and use.


The rise of “Ozempic face” underscores a broader debate about the use of medical treatments for cosmetic purposes and the societal obsession with weight loss. As this trend grows, it is crucial for individuals to consider the long-term health implications and seek advice from healthcare professionals before embarking on any treatment not prescribed for its original intent. The allure of quick cosmetic fixes should not overshadow the importance of responsible medical guidance.

Photo Credit: Women World

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