South Korean actor Lee Dong-gun recently revealed his diagnosis of ankylosing spondylitis (AS), an autoimmune condition that affects the spine and can even cause inflammation in the eyes. Here is what the disease means, and how those living with it can manage life after diagnosis.
At the end of last month, South Korean actor Lee Dong-gun was diagnosed with ankylosing spondylitis (AS), a disease afflicting up to over 1% of the population across the globe.
This diagnosis was revealed during an episode of My Little Old Boy, a popular entertainment program, for which he turned up with a bloodshot eye.
Upon speaking with the doctor, he was open about how frequently he experienced uveitis, a type of eye inflammation that affects the uvea, or the middle layer of tissue in the eye, which can result in redness, pain, and a decline in vision.
In response, the doctor proposed that the 45-year-old could be suffering from this rare condition.
What is Ankylosing Spondylitis?
AS is a chronic autoimmune disease, which means that the immune system attacks the body, instead of protecting it as it was designed to do. It mainly affects one’s spine, though it can also impact other joints, including those in the shoulders, hips and knees.
It can lead to a variety of physiological problems, including:
Reduced Mobility and Chronic Pain
The most common symptoms of AS are stiffness and pain in the spine, especially in the lower back where inflammation can sit. It can be compounded after waking up in the morning, or after being in repose for too long.
The inflammation can fuse bones together, leading to a reduced ability for movement. Over time, it can also result in a deeper curving of your spine, worsening your posture.
Other Systemic Effects
AS can also affect other organs, such as the eyes and skin. This includes uveitis, which is what Lee Dong-gun is experiencing, and psoriasis, the development of itchy patches on the body.
People with this condition can also develop anaemia or general fatigue.
In addition, the inflammation can cause a constriction of the lungs due to the fusing of joints by the ribs, thus resulting in breathing difficulties.
Reduced Mental Health
Living with AS, or any chronic condition, can be distressing and isolating. The constant pain and fatigue can also make daily tasks difficult to perform, and cause people to engage less in social activities.
Many people with AS experience depression, isolation, and anxiety due to persistent fatigue or limitations in mobility.
Can Ankylosing Spondylitis Be Cured?
Unfortunately, there is currently no cure for AS, nor is it a preventable condition.
This could be partly attributed to the fact that its exact cause is still unclear. However, research posits that it has a genetic component. This means that for those with a family history of AS, it’s important to be diagnosed as soon as possible, especially if one starts to display pain symptoms associated with the back or the eyes. Early intervention can make a significant difference in slowing down or even stopping the progression of the disease.
Regardless, there are still many individuals who are inflicted with this condition, despite not having a family background that involves AS – as is the case with Lee Dong-gun.
“So I got it by rare chance, then,” he lamented.
A Lifelong Illness, An Improved Lifestyle
While AS cannot be cured, its deteriorating effect on the body means that being able to manage the disease effectively is crucial.
“Since this disease is genetic, it needs lifelong management,” the doctor explained to Lee Dong-gun. “Even if you feel fine now, lack of management can cause problems.”
Strategies for managing AS include:
An Exercise Regime
The risk of joint fusion increases as a result of a lack of movement. Staying active can help prevent this, reduce pain and stiffness, and boost your breathing capacity.
Focus on exercises that promote strength, balance and flexibility. This can comprise core workouts, weight and resistance training, and yoga.
Practicing Good Posture
Keep your head level and your chin up if it tends to fall forward, and try to avoid slouching. Make sure to intersperse long periods of inactivity with some movement, like a short walk or some seated stretching.
When you’re sleeping, try to lie flat on your back, or put a pillow between your knees if you’re on your side to support spinal alignment.
A Healthy Diet
A diet rich in calcium and vitamin D can enhance bone health. It’s also important to incorporate fruits, vegetables, whole grains, and lean proteins, as well as omega-3 fatty acids to help with the inflammation.
Reduce your intake of fried or heavily-processed foods, and limit smoking and alcohol consumption.
Prioritising Sleep
Poor sleep can aggravate the symptoms of AS. To improve sleep quality, follow sleep hygiene practices like having a comfortable sleep environment and a consistent bedtime routine.
You can also look for a mattress that supports your back and other joints.
Managing Ankylosing Spondylitis Effectively
After diagnosis, a healthcare professional may also prescribe medical treatment and physical therapy. With medical treatment, physical therapy, and lifestyle adjustments, people living with AS can maintain mobility and lead fulfilling lives.
Lee Dong-gun’s openness about his condition has shone a light on a disease often overlooked until it causes significant damage. His story is a reminder that listening to your body, even for something as small as an eye inflammation, can make all the difference.
With the right approach, individuals with AS, like Lee Dong-gun, can work through their symptoms, preserve mobility, and live rich, fulfilling lives.
External References
- Cleveland Clinic. (2023, December 19). Ankylosing Spondylitis. Retrieved from: https://my.clevelandclinic.org/health/diseases/ankylosing-spondylitis
- Jividen, S. (2025, July 7). 7 Self-Care Tips for Managing Ankylosing Spondylitis. Health. Retrieved from: https://www.health.com/ankylosing-spondylitis-self-care-8655970
- Mayo Clinic. (2023, September 21). Ankylosing spondylitis. Retrieved from: https://www.mayoclinic.org/diseases-conditions/ankylosing-spondylitis/symptoms-causes/syc-20354808
- Mayo Clinic. (2025, September 20). Uveitis. Retrieved from: https://www.mayoclinic.org/diseases-conditions/uveitis/symptoms-causes/syc-20378734
- Pietrangelo, A. (2018, September 17). The Effects of Ankylosing Spondylitis on the Body. Healthline. Retrieved from: https://www.healthline.com/health/60199
- The Straits Times. (2025, September 30). Actor Lee Dong-gun diagnosed with rare progressive inflammatory disease on reality show. Retrieved from: https://www.straitstimes.com/life/entertainment/actor-lee-dong-gun-diagnosed-with-rare-progressive-imflammatory-disease-on-reality-show
